High Performance Computing Resources

Center for Computational Omics and Research for Translational EXcellence is Meharry’s advanced on-premise data center. This HPC infrastructure enables high throughput computation, supports cutting edge AI and machine learning model development, and powers secure integration and analysis of large-scale data. This center provides essential computing architecture to meet the demands of medical scientific research and data intensive applications.

CORTEX features four HPC clusters: [flesh these out with more details]

  • Axon: First Meharry supercomputer (Ada).
  • Dendron: Quartet supercomputer via NSF MRI funding.
  • Cognos: CPU-intensive Dell HPC for large-scale analytics via HEERF funding.
  • Synapse: GPU-intensive Dell HPC for AI model training (HRSA-funded).
High-Performance Computing

Key Features

  • Computing Power
    The Ada/Midframe leverages parallel computing architecture to effectively handle computationally intensive tasks.
  • Scalability
    The system offers scalability, allowing users to dynamically assign computing resources to fit their requirements.
  • Data Handling
    The Ada/Midframe combines data management methods and optimized data analysis tools that enable users to swiftly process and analyze vast amounts of data.

Computing Infrastructure

Our high-performance network is comprised of the Ada and Midframe supercomputing clusters. Both clusters have a head node and four compute nodes. The operating system is Suse Linux Enterprise and InfiniBand serves as the network fabric, providing high-speed communication between compute nodes.

Ada Head Node Specifications

  • 2 EPYC CPU (128 cores total)
  • 4TB memory
  • 2TB NVME Global File system
  • 192TB Disks Space. 

Specifications for each Ada Compute Node

  • 1 EPYC CPU (64 cores total)
  • 512GB local memory
  • 0.8TB NVME Local File system

Midframe Head Node Specifications

  • 2 EPYC CPU (128 cores total)
  • 4TB memory
  • 2TB NVME Global File system
  • 192TB Disks Space. 

Specifications for each Ada Compute Node

  • 2 EPYC CPU (128 cores total
  • 2TB local memory
  • 0.8TB NVME Local File system
  • 192TB Storage Space

Software Environment

  • Operating System: Suse Linux Enterprise for High-Performance version 15-SP4
  • Compiler Suite: gcc (SUSE Linux) 7.5.0
  • Parallel Programming Models: OpenMP
  • Job Scheduler: SLURM (to be deployed soon)

Other Software Packages

  • 5.1 AI and Data Science Suite
  • R / Rstudio
  • PostgreSQL
  • MIOpen Library
  • Tensorflow 5.2 Bioinformatics Suite
  • Pytorch
  • BioPython
  • Pysam
  • Pymol
  • Rosetta 5.3 Julia Suite

Resources Available to Users

The Ada/Midframe gives a comprehensive resource to support the computational needs of its faculty and students. These resources include:

  • Researchers can submit batch jobs to the system.
  • This system combines a high-speed interconnect to enable the communication and data transfer between compute nodes, supporting faster parallel computations.
  • A distributed parallel file system ensures users have fast and reliable access to files during computations.
  • This system offers a selection of software libraries and tools specifically tailored for medical and health sciences research.
  • A dedicated support team is available to provide technical assistance, guidance and troubleshooting issues to users.

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